As part of the on-going efforts to arrive at possible solutions for Coronavirus disease, the Indian AYUSH ministry has approved a proposal for a clinical study to assess the role of Vasa Ghana, Guduchi Ghana and Vasa-Guduchi Ghana in therapeutic management of symptoms in Covid-19 positive cases.

This will be a “randomized, open label three armed” study, and will be conducted at the All India Institute of Ayurveda (AIIA), New Delhi, in collaboration with the IGIB unit of CSIR.

“The detailed proposal with methodology including outcome measures, clinical and laboratory parameters, the logistics of the research has been prepared. The study will use a unique Case Report Forum (CRF), suitable for Ayush mode research. The CRF and study protocol has also been peer reviewed by experts from different domains including modern medicine and their suggestions have been incorporated. The study will be undertaken subject to the required approvals like that of the Institutional Ethics Committee (IEC),” the ministry said in a statement.

The clinical research would look into the efficacy/action of mono-herbal formulations of whole extracts of Vasa (Adhatoda vasica Linn) and Guduchi (Tinospora cordifolia) respectively, and polyherbal formulation of Vasa-Guduchi whole extract on therapeutic management of SARS-CoV2 positive asymptomatic and/ or mild Covid-19 symptomatic cases. The impact of the said formulations on the speed of viral replication will be assessed. It would also ascertain whether the said mono-herbal and polyherbal formulations can alter the expression profiles of key bio markers associated with Covid-19 disease.

Vasa and Guduchi are time tested herbs in Indian healthcare traditions, used in a variety of disease conditions. The outcome of this study would therefore be of considerable interest to the entire Ayush Sector.